ANTIBIOTICE S.A.


BVB TICKER:  ATB

 Address:  IASI, jud. IASI, str. Valea Lupului nr.1

 Phone: +40 232220040

www.antibiotice.ro

 Date: 24.07.2007 


About the company

With a half a century of tradition in the field of generic drug manufacturing and a complex portfolio comprising over 120 medicines covering 11 therapeutic classes, Antibiotice SA is the only producer of injectable cephalosporins and the main producer of antiinfectives in Romania. In addition, Antibiotice is leader on the domestic market of the solutions and suspensions for injection filled into vials in terms of physical units.

The quality of the company products is attested by the Good Manufacturing Practice (GMP) Certificate, the Certificate of Suitability to the European Pharmacopoeia and acceptance by the Food and Drug Administration (FDA) for the US and Canadian markets.

At present, the company has 9 production lines, all GMP certified, for the manufacturing of 7 dosage forms (powders for injectable solutions and suspensions, capsules tablets, ointments, gels, creams and suppositories) and of the active ingredient Nystatin.

Company`s portfolio comprises medicines of human use, of veterinary use, active ingredients and natural fertilizers. Among the best known brands of medicines made by Antibiotice we can mention: Moldamin®, Piafen®, Cutaden®, Sinerdol®, Hemorzon®. Sinopryl®, Ceftriaxon®, Ampiplus®, recommended for a wide range of disorders.

At present, Antibiotice holds 130 trade marks in the country registered with the Romanian State Office for Inventions and Trademarks, and 20 international trade marks registered in over 45 countries worldwide.

History

1955-1959 - In December 1955 came into being the first Romanian pharmaceutical company. Shortly after, Antibiotice became the first East European company producing on large scale Alexander Fleming’s famous discovery: penicillin. Four years later, the streptomycin production facility started operating and the manufacturing of ointments, creams and suppositories was initiated.

1960-1977 – The manufacturing lines for active ingredients were developed (e.g. erythromycin, oxytetracycline, tetracycline, griseofulvin, sinerdol, lysine). Antibiotice became the only manufacturer of sterile products for parenteral use (injection) in Romania.

 The acceptance of the Streptomycin manufacturing facility by the Food and Drug Administration (the US regulatory authority) in 1977 opened the way to the international market.

1977-1989 – In the 80’s, Antibiotice already exported 50% of its production. Thus, the active ingredients manufactured in Iasi became an essential element of a wide range of medicines produced both in the country and worldwide. A number of 44 letters patents in the pharmaceutical field were registered and 600 technical innovations were implemented in production in the same period.

1990 – As a result of the changes at macroeconomic level, the management of the company reoriented the production of pharmaceuticals. The finished dosage forms gained the main position in the product portfolio, the active ingredients being manufactured to be used in developing new pharmaceutical forms. In a short while, the introduction of over 30 pharmaceutical products in manufacture placed the company amongst the top Romanian manufacturers of anti-infective medicines.

1993-1997 – Major investments exceeding 8 million Euros were carried out to the purpose of revamping and purchasing state-of-the-art, competitive equipment. Antibiotice ascends in the top 5 world producers of penicillin and penicillin derivatives.

1997-2000 – Constantly concerned with the quality of its products, in 1997 the company started to implement an effective quality assurance system requiring the strict control of the manufacturing processes. Thus, in 1999, Antibiotice became the first Romanian producer to obtain the Good Manufacturing Practice (GMP) Certificate for the facility of powders for injectable medicines. The ascendant financial evolution resulted in an important achievement: the company was listed to the Stock Exchange Bucharest.

2000-2004 – The continuous investments in research, people training, and quality as well as in updating the production lines and working areas turned Antibiotice into a profitable, dynamic company with a healthy economic growth.

2005 – Upon celebrating 50 years of activity, Antibiotice launched a new corporate brand identity. Starting with December, the company had a new logo and a new slogan which reflect the massive transformations undergone by the company in terms of organizational structure, technology, and culture.

January 2006 – LLOYD’S REGISTER QUALITY ASSURANCE granted Antibiotice the ISO 9001:2000 certificate for the Quality Management System in the field of pharmaceutical product manufacturing.

Major shareholders

Shareholder

Shares

Percent

A.V.A.S.

241,174,148

53.02%

OTHER SHAREHOLDERS

144,849,455

31.84%

S.I.F. OLTENIA

45,923,746

10.10%

NON-RESIDENT CLIENTS-CITIBANK

22,949,942

5.05%

 

Total No. of Shares

454,897,291

Nominal Value

0.1000

Share Capital

45,489,729.10

  

Annual financial information (Key financials)

 

2006(RON)

2005(RON)

2004(RON)*

 Fixed assets - Total  

  106,793,221.00

  85,596,263.00

  80,982,640.00

 Current assets - Total  

  153,595,074.00

  126,159,137.00

  107,946,721.20

 

 

 

 

 Debtors - due within one year  

  68,662,036.00

  54,405,204.00

  58,483,297.10

 Current assets/Net current liabilities  

  85,181,691.00

  71,819,222.00

  49,667,259.00

 Total assets less current liabilities  

  183,101,563.00

  149,006,512.00

  122,993,261.20

 Debtors - due after more than one year  

  2,547,890.00

  1,825,211.00

  4,434,342.80

 Revenues in advance  

  8,873,349.00

  8,409,022.00

  7,660,604.40

 

 

 

 

 Subscribed paid up capital  

  45,489,729.00

  45,489,729.00

  40,435,314.80

 Shareholders equity - Total  

  177,059,654.00

  143,580,488.00

  117,358,918.40

 

 

 

 

 Total receivables  

  106,591,713.00

  98,496,131.00

  82,976,615.30

 Total liabilities  

  71,209,926.00

  56,230,415.00

  62,917,639.90

 

 

 

 

 Net turnover  

  195,677,945.00

  163,497,747.00

  136,028,514.50

 

 

 

 

 Operating income - Total  

  193,392,713.00

  164,867,029.00

  139,796,503.60

 Operating expenses - Total  

  164,311,849.00

  138,522,664.00

  122,903,619.80

 Operating result  

  29,080,864.00

  26,344,365.00

  16,892,883.80

 

 

 

 

 Financial income - Total  

  4,355,603.00

  1,652,932.00

  3,536,033.90

 Financial expenses - Total  

  3,362,907.00

  4,272,442.00

  2,851,956.40

 Financial result  

  992,696.00

  -2,619,510.00

  684,077.50

 Current result  

  30,073,560.00

  23,724,855.00

  17,576,961.30

 

 

 

 

 Extraordinary income  

  0.00

  0.00

  0.00

 Extraordinary expenses  

  0.00

  0.00

  0.00

 Extraordinary result  

  0.00

  0.00

  0.00

 

 

 

 

 Total revenues  

  197,748,316.00

  166,519,961.00

  143,332,537.50

 Total expenses  

  167,674,756.00

  142,795,106.00

  125,755,576.20

 

 

 

 

 Gross result  

  30,073,560.00

  23,724,855.00

  17,576,961.30

 Net result  

  23,839,146.00

  19,678,661.00

  12,424,687.00

 Result per share  

  -

  -

  0.0307

 

 

 

 

 Back payments - Total  

  14,350,243.00

  15,465,882.00

  8,929,856.90

 Back payments for suppliers - Total  

  11,338,449.00

  12,533,610.00

  6,778,473.10

 Back payments of liabilities to the social insurance budget  

  0.00

  0.00

  0.00

 Taxes which are not paid to the State budget upon payment date  

  0.00

  0.00

  0.00

 

 

 

 

 Average number of employees (only full time employees)  

  1556

  1650

  1753